These terms govern the PharmStarsTM accelerator. Please read them carefully before applying to participate.
1. Program Overview
PharmStars is the pharma-focused accelerator for digital health startups. For each cohort, 10 startups will be selected to participate in PharmaU(TM), a 10-week educational and mentoring program led by PharmStars staff and Mentor Advisors. After the initial in-person Launch Event in Boston, Massachusetts, all PharmaU classes and mentoring occur virtually. Any startup, no matter where it is located, may apply.
PharmaU culminates with an exclusive Startup Showcase, where startups present to PharmStars’ pharma members. Additionally, private one-on-one meetings between startups and pharma members will be arranged by PharmStars. The Startup Showcase takes place in-person in Boston, MA. Details are shared with the cohort participants in advance of the event.
2. PharmaU
PharmaU is PharmStars’ proprietary educational program, developed and led by PharmStars’ professional staff. PharmaU has two components for startups:
- a comprehensive, structured curriculum to teach startups what they need to know about pharma to successfully engage them as clients
- individualized coaching and mentoring for startups on the development of their business model and value proposition
Classes are interactive and focus on important pharma topics, including: the internal structure and functions of pharma, pharma business models, regulatory drivers, pharma-startup deal structures, and current industry trends. The curriculum is comprised of asynchronous videos and classes taught by the PharmStars expert staff and occasional external speakers. There are ample opportunities for peer-to-peer sharing and discussion. PharmStars’ pharma member representatives participate in “Fireside Chats” and “Members’ Panels” for the startups throughout PharmaU. Classes and mentoring meetings are held virtually.
3. Pharma Members
PharmStars is supported by its “pharma members” - forward-thinking pharma companies that are committed to digital innovation. Our pharma members have helped define our theme, reflecting the types of startups with whom they wish to engage. However, startups are selected entirely by PharmStars staff.
Each pharma member has designated a liaison (Champion), at the director-level or higher, with strong internal relationships and a passion for working with startups. The Champion serves as the connection between their company and PharmStars’ startups. Champions commit to attending the Startup Showcase, meeting one-on-one with startups, and assisting in connecting startups that interest their firm with the appropriate contacts.
4. The Selection Process
Applicants:
PharmStars is designed to support digital health startups that:
- want to engage pharma as clients, customers, or partners
- would benefit from priority access to our pharma members
- recognize the importance of an enhanced understanding of pharma
The ideal startup candidate would:
- be interested in receiving education, mentoring, and coaching to create a clearer pharma-specific value proposition and better pitch to engage a pharma audience
- have a prototype or product ready to be offered to, and used by, pharma
- have an innovation related to the cohort theme
- benefit from introductions to pharma decision makers
- Novel collection and application of RWE
- RWE endpoint design
- Biomarkers
- RWE generation and data sources
- Data capture & remote monitoring
- RWE data analysis
Selection Criteria:
- Fit: Offers a promising innovation in the theme area described on the home page
- Product Stage: Has a developed product or viable prototype that can be immediately adopted by pharma
- Need: Has not yet broadly and successfully engaged with pharma and would benefit from the education and coaching that PharmStars offers
Eligibility:
- All applicants must be 18 years or older.
- Startups with and without pharma clients are welcome to apply. PharmStars is of value even to startups that have had some measure of success in previously engaging pharma as clients and customers.
- Startups that have participated in other accelerators are welcome to apply.
5. The Application Process
- Applications must be completed in one sitting, as they cannot be saved in draft form. However, a downloadable copy of the application is available.
- Applications must be completed and submitted prior to the application deadline.
- Applications will not be returned to the applicant after submission.
Semi-Finalists Selection and Participation Deposit:
Startups that advance to the semi-finalist phase will be notified by email on a rolling basis throughout the application and selection period. Upon notification, startups advancing to the semi-finalist phase will have 3 business days to:
- Sign and return the “Participation Terms and Conditions Acknowledgement Form” acknowledging familiarity with participation terms and conditions of the program; and
- Provide a $500 refundable Participation Deposit.
○ If the startup is not selected to participate, the deposit will be fully refunded within 30 days of notification.
○ If the startup is accepted to participate, the deposit will be credited toward the $6,000 tuition deposit required for participation or forfeited if the accepted startup declines to participate.
Startups that do not return the signed Participation Terms and Conditions Acknowledgement Form or do not supply the required Participation Deposit within 3 business days will not be given further consideration for participation in this cohort.
PharmStars invests significant resources in selecting finalists to participate in each cohort. The purpose of the Participation Deposit is to ensure that those resources are focused on applicants who are committed to participating in the program should they be selected.
Finalist Notification and Confirmation of Participation:
Applicants selected to participate in the upcoming cohort will be notified by email by August 26, 2026. They will have two business days to confirm their intent to participate and pay the balance of their tuition. Otherwise, the invitation will be extended to another applicant.
Communications and Timing:
- If selected as a semi-finalist, a startup must sign the Participation Terms and Conditions Acknowledgement Form and provide the $500 Participation Deposit within three business days.
- If selected as a finalist, a startup must confirm their participation and complete their tuition deposit payment within two business days.
6. Investment + Tuition
Investment in Participating Startups:
Each startup that successfully completes the PharmStars accelerator program will receive an investment of $100,000 USD in the form of a SAFE (Simple Agreement for Future Equity). The SAFE is an agreement between the startup and the PharmStars Ventures Fund (PSVF) that will convert the investment into shares of the most senior share class in a subsequent equity funding round or liquidity event. The SAFE is a form of a loan that is simpler than traditional convertible notes.
The PSVF SAFE terms include:
- no specified valuation cap
- a 20% discount on the subsequent equity price
For reference, the full terms of the US SAFE can be seen
here, and the required side letter that also must be executed can be found
here. The SAFE is the standard Y Combinator uncapped SAFE. The side letter includes a few PharmStars Ventures Fund modifications. These documents are not open for negotiation and need to be signed as written. Minor modifications may be needed for the SAFE for non-US-based startups.
To qualify for this investment the two primary representatives from the startup must successfully complete the PharmStars program which is defined as:
- 80% or greater participation in virtual classes and mentoring sessions
- Completion of the asynchronous video classes (approximately 8 hours)
- Creation of a PharmStars approved, pharma-focused pitch deck - developed during the program through projects supported by PharmStars mentors and staff
- A pitch presentation at the Startup Showcase
The SAFE investment will be issued approximately a month after the Startup Showcase.
Only startups from countries in which SAFEs are a legal will be accepted into the program.
Tuition:
Tuition in the PharmStars PharmaU program is $35,000 USD covering participation of 2-4 startup representatives. Startups are required to pay a $6,000 tuition deposit upon acceptance into the program. The balance of tuition will be due at the time of program completion.
For startups that successfully complete the program and receive a SAFE investment from the PSVF, the outstanding tuition balance can be paid out of the SAFE investment amount.
7. Startup Participation Terms
Representatives:
Each startup is expected to send at least two and up to four representatives to PharmaU. Representatives must be full-time employees (not consultants) with decision-making authority with regard to negotiating and signing contracts with prospective pharma clients. Ideally, this is the startup’s CEO and one or two other members of the senior leadership team. All representatives must be at least 18 years old.
Attendance:
- PharmaU: Because our curriculum is tightly integrated, startup representatives are expected to attend all weekly PharmaU classes and personalized mentoring meetings. Attendance at approximately 45 minutes of each week’s classes will be optional.
- Launch Event: Startup participants are expected to attend the in-person cohort Launch Event. Exceptions will be made for special circumstances.
- Startup Showcase: Startups are expected to present at this members-only event at the end of the semester.
- Member Meetings: Startups are expected to participate in one-on-one meetings requested by pharma members at the Startup Showcase.
Timing:
- Classes will be held virtually Mondays and Thursdays from 12:00-1:30 p.m. ET. There will be asynchronous video classes that participants watch at their convenience before their due dates. Members’ Panels and Fireside Chats will also take place during class time.
- Startups will select mutually agreeable meeting times with PharmStars staff for weekly mentoring meetings.
8. Timeline for Fall 2026 Cohort
- Applications due: July 12, 2026 (11:59 p.m. ET)
- Semi-finalist notifications: Rolling basis
- Semi-finalist forms and deposit due: three days after notification of status
- Finalist acceptance notifications: by August 26, 2026
- Cohort participation commitments due: two days after notification of acceptance
- In-person Launch Event: September 9-10, 2026
- PharmaU virtual classes: September 14 - November 5, 2026
- Startup Showcase: Mid-November 2026
9. Startups Engagement with Pharma
PharmaU is designed to educate and empower digital health startups. The knowledge and mentoring offered through PharmaU will equip startups to refine, enhance, and sometimes pivot their business models. Graduating startups will be well-positioned to successfully engage with pharma. To enable startups to fully prepare for their initial meetings and to increase the probability of a successful “initial meeting” with pharma members, contact between startups and members will be restricted to PharmStars-moderated engagements while PharmaU is in session.
Startups will gain tremendous insight into the functioning of pharma companies over the course of PharmaU, which may influence their plans for how to best engage pharma. As a result, startups may pivot their business model and/or description of their value proposition. It is, therefore, often in the best interest of participating startups to limit initiation of new contacts with pharma until they have completed the accelerator. To take full advantage of our accelerator’s offerings, startups are strongly discouraged from starting new pharma business engagements from the time of acceptance into PharmStars until the conclusion of the program.
Blackout Period:
10. Confidentiality
- Startups are required to keep PharmaU curriculum and materials confidential.
- Startups are expected to share only non-confidential information with PharmStars.
11. Use of Name
- PharmStars has the right to publicize names of all participating startups.
- PharmStars has the right to use startups’ names and/or logos on the PharmStars website and in promotional materials.
12. Contacting PharmStars
- For any questions or technical issues, please email info@pharmstars.com.
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